The work purpose is the investigation of the clusterization tendencies in the modern world economy. The research subject is clusterization processes in their interrelation with globalization and regionalization. A monographic method is used as the methodological basis of the research. The essence of globalization and regionalization is briefly described, common features and contradictions of the given phenomena are shown. The branch and territorial specificity of the clusterization is analyzed. The reasons hampering the efficient cluster development in a number of countries of the world (in particular, in Russia and on the post-Soviet territory) are identified. Some examples of the transboundary cluster operation are considered. The conclusion on the interrelation of the globalization and regionalization processes, and cluster approach development is formulated. The research results can be used for the in-depth study of the clusterization process, the development of practical recommendations on the cluster policy implementation at the national and regional level.